GNAI3

Across TCGA patient cohorts, GNAI3 protein abundance is significantly associated with the RNA expression of many other genes, with 10,014 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GNAI3-associated genes across cancer lineages are ZFP37, PSMA5, and CPED1. Each is linked with GNAI3 in more than 4 cancer types. Because this analysis shows association rather than direction, both GNAI3-to-partner and partner-to-GNAI3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNAI3 versus ZFP37 in OV, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNAI3→partner) and Y-score (partner→GNAI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZFP37 →	-0.612	-0.213	<.001	<.001	3	5
HNSC	PSMA5 →	+0.496	+0.279	.001	<.001	3	5
HNSC	CPED1 →	-0.664	-0.227	.005	.003	3	4
HNSC	PTGIS →	-1.228	-0.288	<.001	<.001	3	4
UCEC	SPARCL1 →	-1.066	-0.282	.001	<.001	3	4
HNSC	TNXB →	-0.983	-0.208	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,014 associations by consensus.

GNAI3 vs ZFP37 — OV

Explore this scatter interactively →