GNAI2P2

Across TCGA pan-cancer cohorts, GNAI2P2 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated GNAI2P2 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher GNAI2P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GNAI2P2 expression acts as an unfavorable survival marker, although some lineages such as ESCA and BRCA show a favorable association.

DLBC, ESCA, and KIRC are the cancer types where GNAI2P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Tertile	II,III,IV	0.172	0.949	<.001	95	view →
ESCA	DFS	Quartile	III,IV	0.781	0.257	.005	63	view →
KIRC	DFS	Tertile	II,III,IV	0.275	0.683	<.001	54	view →
COAD	OS	Tertile	All	0.181	0.803	.001	45	view →
THCA	DFS	Tertile	All	0.586	0.921	<.001	36	view →
ACC	OS	Tertile	All	0.114	0.892	<.001	36	view →
PAAD	DFS	Tertile	All	0.246	0.479	.014	27	view →
BRCA	OS	Tertile	All	0.984	0.919	.025	24	view →
SKCM	OS	Tertile	All	0.170	0.344	.001	18	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	18	view →
OV	DFS	Tertile	III,IV	0.434	0.548	.028	12	view →
LUSC	OS	Tertile	II,III,IV	0.175	0.685	.024	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

GNAI2P2–DLBC (OS)

Open the DLBC breakdown →