GNA15

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GNA15 protein abundance is significantly associated with the RNA expression of many other genes, with 10,253 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GNA15-associated genes across cancer lineages are MEFV, CCDC136, and LIPN. Each is linked with GNA15 in more than 2 cancer types. Because this analysis shows association rather than direction, both GNA15-to-partner and partner-to-GNA15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GNA15 versus MEFV in GBM, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNA15→partner) and Y-score (partner→GNA15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMMEFV →+0.958+0.718.002.00133
LSCCCCDC136 →-0.927-0.562<.001<.00133
HNSCLIPN →+0.871+0.579.001<.00133
UCECHCAR3 →+1.035+0.785.003.00733
LSCCIFI27 →+1.237+0.447<.001<.00133
LSCCTMEM154 →+0.938+0.443<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,253 associations by consensus.

GNA15 vs MEFV — GBM

Per-sample scatter of GNA15 vs MEFV in GBM (Pearson r = 0.55).

Explore this scatter interactively →

Exploration