GNA15

Across TCGA patient cohorts, GNA15 mutation is significantly associated with the RNA expression of many other genes, with 1,386 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GNA15-associated genes across cancer lineages are RNA5SP411, RNU6-694P, and TTTY8. Each is linked with GNA15 in more than 2 cancer types. Because this analysis shows association rather than direction, both GNA15-to-partner and partner-to-GNA15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by GNA15-low versus GNA15-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNA15→partner) and Y-score (partner→GNA15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+1.110	+2.393	<.001	.002	3	3
LIHC	RNU6-694P →	+0.304	+5.268	<.001	.006	3	3
STAD	TTTY8 →	+0.020	+4.597	<.001	.005	3	2
STAD	RNU5F-6P →	+0.283	+3.396	.007	.009	3	2
HNSC	RN7SKP25 →	+0.203	+5.303	<.001	.006	3	2
UCEC	UHRF1 →	+1.021	+2.595	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,386 associations by consensus.

RNA5SP411 by GNA15 expression — UCEC

Explore this box plot interactively →