GNA13

Across TCGA cell cohorts, GNA13 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,433 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GNA13-associated GO terms across cancer lineages are Negative regulation of beige fat cell differentiation, Positive regulation of organelle assembly, and Rho-activating G protein-coupled receptor signaling pathway. Each is linked with GNA13 in more than 15 cancer types. Because this analysis shows association rather than direction, both GNA13-to-partner and partner-to-GNA13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of beige fat cell differentiation grouped by GNA13-low versus GNA13-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GNA13→partner) and Y-score (partner→GNA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of beige fat cell differentiation →	+0.160	+1.125	<.001	.002	3	16
LUNG_NSCLC_LUSC	Positive regulation of organelle assembly →	+0.062	+0.871	.002	.007	3	13
KIDNEY	Rho-activating G protein-coupled receptor signaling pathway →	+0.208	+0.863	.001	.001	3	13
BLOOD_Leukemia	Regulation of microtubule cytoskeleton organization →	+0.043	+0.610	<.001	<.001	3	13
BONE	Regulation of microtubule depolymerization →	+0.092	+0.410	<.001	.001	3	13
STOMACH	Phosphatidylinositol metabolic process →	+0.054	+0.804	.006	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,433 associations by consensus.

Negative regulation of beige fat cell differentiation by GNA13 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →