GNA13

Across TCGA cell cohorts, GNA13 mutation is significantly associated with the RNA expression of many other genes, with 1,177 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GNA13-associated genes across cancer lineages are TTLL8, OR13D1, and ELOA3DP. Each is linked with GNA13 in more than 1 cancer types. Because this analysis shows association rather than direction, both GNA13-to-partner and partner-to-GNA13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TTLL8 grouped by GNA13-low versus GNA13-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GNA13→partner) and Y-score (partner→GNA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TTLL8 →	+0.003	+4.022	<.001	.006	3	1
LARGE_INTESTINE	OR13D1 →	+0.030	+3.882	<.001	.001	3	1
LARGE_INTESTINE	ELOA3DP →	+0.034	+3.688	<.001	.002	3	1
LARGE_INTESTINE	TAS2R60 →	+0.028	+4.669	<.001	<.001	3	1
BLOOD_Lymphoma	LGALS1 →	-2.900	-3.265	.001	.004	3	1
BLOOD_Lymphoma	DEPDC5 →	+0.797	+3.980	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,177 associations by consensus.

TTLL8 by GNA13 expression — LARGE_INTESTINE

Explore this box plot interactively →