GMPR2

Across TCGA patient cohorts, GMPR2 protein abundance is significantly associated with the RNA expression of many other genes, with 17,494 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GMPR2-associated genes across cancer lineages are NCAPH, DIAPH3, and FOXM1. Each is linked with GMPR2 in more than 7 cancer types. Because this analysis shows association rather than direction, both GMPR2-to-partner and partner-to-GMPR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GMPR2 versus NCAPH in BRCA, with a Pearson correlation of -0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GMPR2→partner) and Y-score (partner→GMPR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NCAPH →	-0.801	-0.345	<.001	<.001	3	8
UCEC	DIAPH3 →	-0.830	-0.248	<.001	.001	3	8
GBM	FOXM1 →	-1.114	-0.346	<.001	<.001	3	7
GBM	CENPF →	-1.410	-0.372	<.001	<.001	3	7
GBM	KIF14 →	-1.244	-0.350	<.001	<.001	3	7
GBM	KIF18A →	-1.039	-0.384	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,494 associations by consensus.

GMPR2 vs NCAPH — BRCA

Explore this scatter interactively →