GMPR2

Across TCGA cell cohorts, GMPR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,647 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GMPR2-associated GO terms across cancer lineages are Protein linear polyubiquitination, Endothelial to hematopoietic transition, and Regulation of intracellular estrogen receptor signaling pathway. Each is linked with GMPR2 in more than 10 cancer types. Because this analysis shows association rather than direction, both GMPR2-to-partner and partner-to-GMPR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein linear polyubiquitination grouped by GMPR2-low versus GMPR2-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GMPR2→partner) and Y-score (partner→GMPR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Protein linear polyubiquitination →	+0.132	+0.765	.007	.006	3	11
BREAST	Endothelial to hematopoietic transition →	+0.106	+0.793	<.001	<.001	3	10
KIDNEY	Regulation of intracellular estrogen receptor signaling pathway →	+0.080	+0.627	.009	.009	3	8
KIDNEY	DNA ADP-ribosylation →	+0.165	+0.835	<.001	.003	3	8
KIDNEY	Golgi organization →	+0.065	+0.891	<.001	<.001	3	7
BREAST	Thiamine metabolic process →	+0.762	+0.484	<.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,647 associations by consensus.

Protein linear polyubiquitination by GMPR2 expression — KIDNEY

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