GMPR

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GMPR RNA expression is significantly associated with the protein abundance of many other proteins, with 11,958 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GMPR-associated proteins across cancer lineages are TRIM68, VPS4B, and MYEF2. Each is linked with GMPR in more than 3 cancer types. Because this analysis shows association rather than direction, both GMPR-to-partner and partner-to-GMPR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GMPR versus TRIM68 in UCEC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GMPR→partner) and Y-score (partner→GMPR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTRIM68 →+0.367+1.050.002<.00134
OVVPS4B →-0.198-1.038.009.00434
HNSCMYEF2 →+0.831+1.009<.001<.00134
BRCAMX1 →+1.099+1.022<.001<.00134
OVOAS3 →+0.735+1.081<.001.00534
HNSCNFIC →+0.338+0.864.001.00834
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,958 associations by consensus.

GMPR vs TRIM68 — UCEC

Per-sample scatter of GMPR vs TRIM68 in UCEC (Pearson r = 0.36).

Explore this scatter interactively →

Exploration