GMPPB

Across TCGA cell cohorts, GMPPB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,566 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GMPPB-associated GO terms across cancer lineages are GDP-mannose biosynthetic process, GDP-mannose metabolic process, and Meiotic chromosome condensation. Each is linked with GMPPB in more than 19 cancer types. Because this analysis shows association rather than direction, both GMPPB-to-partner and partner-to-GMPPB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GDP-mannose biosynthetic process grouped by GMPPB-low versus GMPPB-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GMPPB→partner) and Y-score (partner→GMPPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	GDP-mannose biosynthetic process →	+0.182	+1.096	<.001	.003	3	20
URINARY_TRACT	GDP-mannose metabolic process →	+0.192	+1.273	<.001	.003	3	20
SKIN	Meiotic chromosome condensation →	+0.173	+1.393	<.001	<.001	3	13
URINARY_TRACT	Protein to membrane docking →	+0.110	+0.981	.001	.009	3	12
URINARY_TRACT	Mitochondrial potassium ion transmembrane transport →	+0.160	+1.179	<.001	.002	2	13
BONE	Microtubule polymerization →	+0.098	+0.609	<.001	.003	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,566 associations by consensus.

GDP-mannose biosynthetic process by GMPPB expression — KIDNEY

Explore this box plot interactively →