GMPPB

Across TCGA cell cohorts, GMPPB mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GMPPB-associated genes across cancer lineages are FERD3L and DEFA3. Each is linked with GMPPB in more than 1 cancer types. Because this analysis shows association rather than direction, both GMPPB-to-partner and partner-to-GMPPB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FERD3L grouped by GMPPB-low versus GMPPB-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GMPPB→partner) and Y-score (partner→GMPPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FERD3L →	+0.079	+4.977	<.001	.007	3	1
LARGE_INTESTINE	DEFA3 →	+0.095	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

FERD3L by GMPPB expression — LARGE_INTESTINE

Explore this box plot interactively →