GMPPA

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GMPPA RNA expression is significantly associated with the protein abundance of many other proteins, with 11,405 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GMPPA-associated proteins across cancer lineages are DTYMK, FAM114A1, and COPB2. Each is linked with GMPPA in more than 3 cancer types. Because this analysis shows association rather than direction, both GMPPA-to-partner and partner-to-GMPPA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GMPPA versus DTYMK in LSCC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GMPPA→partner) and Y-score (partner→GMPPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCDTYMK →+0.296+0.277<.001<.00134
LSCCFAM114A1 →+0.365+0.314<.001<.00134
BRCACOPB2 →+0.175+0.316<.001.00134
UCECARCN1 →+0.181+0.502<.001<.00134
CCRCCPARP4 →+0.391+0.279<.001<.00134
BRCAARMCX3 →+0.327+0.334<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,405 associations by consensus.

GMPPA vs DTYMK — LSCC

Per-sample scatter of GMPPA vs DTYMK in LSCC (Pearson r = 0.30).

Explore this scatter interactively →

Exploration