GMPPA

Across TCGA cell cohorts, GMPPA RNA expression is significantly associated with the go_rna of many other GO terms, with 3,800 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GMPPA-associated GO terms across cancer lineages are Regulation of protein exit from endoplasmic reticulum, Positive regulation of protein exit from endoplasmic reticulum, and COPI-coated vesicle budding. Each is linked with GMPPA in more than 14 cancer types. Because this analysis shows association rather than direction, both GMPPA-to-partner and partner-to-GMPPA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein exit from endoplasmic reticulum grouped by GMPPA-low versus GMPPA-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GMPPA→partner) and Y-score (partner→GMPPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of protein exit from endoplasmic reticulum →	+0.124	+0.608	<.001	.002	3	14
LIVER	Positive regulation of protein exit from endoplasmic reticulum →	+0.141	+0.652	<.001	.002	2	15
BLOOD_Myeloma	COPI-coated vesicle budding →	+0.135	+0.942	<.001	.001	3	13
BLOOD_Myeloma	Golgi transport vesicle coating →	+0.135	+0.942	<.001	.001	3	13
BLOOD_Myeloma	COPI coating of Golgi vesicle →	+0.135	+0.942	<.001	.001	3	13
LUNG_NSCLC_LUAD	Nucleotide-sugar biosynthetic process →	+0.072	+0.665	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,800 associations by consensus.

Regulation of protein exit from endoplasmic reticulum by GMPPA expression — KIDNEY

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