Across TCGA patient cohorts, GMNC mutation is significantly associated with the RNA expression of many other genes, with 302 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GMNC-associated genes across cancer lineages are RN7SL301P, IGKV1D-13, and LIN7C. Each is linked with GMNC in more than 1 cancer types. Because this analysis shows association rather than direction, both GMNC-to-partner and partner-to-GMNC results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GMNC→partner) and Y-score (partner→GMNC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL301P →	+0.136	+2.546	.008	.004	3	1
UCEC	IGKV1D-13 →	+2.261	+3.483	<.001	.002	3	1
UCEC	LIN7C →	+0.720	+3.606	.001	.001	3	1
UCEC	CCDC15 →	+0.431	+3.617	.009	.001	3	1
UCEC	SAP18 →	+0.362	+3.371	.007	.004	3	1
UCEC	MBIP →	+0.768	+3.595	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 302 associations by consensus.

Exploration

GMNC survival (RNA) · tumor vs normal (RNA) · all GMNC data types