Across TCGA cell cohorts, GMNC mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GMNC-associated genes across cancer lineages are CD300H, HRG, and ODF1. Each is linked with GMNC in more than 1 cancer types. Because this analysis shows association rather than direction, both GMNC-to-partner and partner-to-GMNC results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GMNC→partner) and Y-score (partner→GMNC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CD300H →	+0.033	+4.415	<.001	.007	3	1
BLOOD_Leukemia	HRG →	+0.353	+3.855	<.001	.007	3	1
BLOOD_Leukemia	ODF1 →	+0.064	+3.944	.001	.006	3	1
BLOOD_Leukemia	ZIC3 →	+0.015	+4.060	<.001	.003	3	1
BLOOD_Leukemia	DCLK3 →	+0.155	+3.769	.005	.008	3	1
BLOOD_Leukemia	INSM2 →	+0.186	+3.769	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

GMNC survival (RNA) · tumor vs normal (RNA) · all GMNC data types