GMIP

Across TCGA patient cohorts, GMIP protein abundance is significantly associated with the RNA expression of many other genes, with 23,075 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GMIP-associated genes across cancer lineages are CYTH4, CSF2RB, and IL2RB. Each is linked with GMIP in more than 8 cancer types. Because this analysis shows association rather than direction, both GMIP-to-partner and partner-to-GMIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GMIP versus CYTH4 in GBM, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GMIP→partner) and Y-score (partner→GMIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYTH4 →	+0.983	+0.439	<.001	<.001	3	9
UCEC	CSF2RB →	+1.199	+0.326	<.001	<.001	3	9
OV	IL2RB →	+0.974	+0.263	.006	.007	3	9
OV	GZMH →	+1.321	+0.308	.003	.002	3	9
UCEC	SIRPB1 →	+0.748	+0.378	<.001	<.001	3	9
HNSC	HCK →	+1.122	+0.378	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,075 associations by consensus.

GMIP vs CYTH4 — GBM

Explore this scatter interactively →