GMFG

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GMFG protein abundance is significantly associated with the RNA expression of many other genes, with 20,509 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GMFG-associated genes across cancer lineages are CYTH4, NCF4, and CSF2RB. Each is linked with GMFG in more than 8 cancer types. Because this analysis shows association rather than direction, both GMFG-to-partner and partner-to-GMFG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GMFG versus CYTH4 in GBM, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GMFG→partner) and Y-score (partner→GMFG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCYTH4 →+1.183+0.859<.001<.00139
GBMNCF4 →+1.326+0.939<.001<.00139
GBMCSF2RB →+1.221+0.936<.001<.00139
UCECIL2RB →+1.105+0.646<.001<.00139
GBMTLR8 →+1.233+0.776<.001<.00139
UCECCORO1A →+1.148+0.501.001.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,509 associations by consensus.

GMFG vs CYTH4 — GBM

Per-sample scatter of GMFG vs CYTH4 in GBM (Pearson r = 0.79).

Explore this scatter interactively →

Exploration