GMFBP1

Across TCGA patient cohorts, GMFBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,845 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GMFBP1-associated GO terms across cancer lineages are Negative regulation of small molecule metabolic process, Ribosome disassembly, and GMP metabolic process. Each is linked with GMFBP1 in more than 8 cancer types. Because this analysis shows association rather than direction, both GMFBP1-to-partner and partner-to-GMFBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of small molecule metabolic process grouped by GMFBP1-low versus GMFBP1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GMFBP1→partner) and Y-score (partner→GMFBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of small molecule metabolic process →	+0.036	+0.172	.003	.003	3	9
UCEC	Ribosome disassembly →	+0.040	+0.071	<.001	<.001	3	9
ESCA	GMP metabolic process →	+0.064	+0.278	<.001	<.001	3	8
STAD	Response to dsRNA →	+0.047	+0.167	<.001	<.001	3	8
ESCA	Carbohydrate derivative transport →	+0.029	+0.200	<.001	<.001	3	8
UCEC	RNA 3'-end processing →	+0.038	+0.077	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,845 associations by consensus.

Negative regulation of small molecule metabolic process by GMFBP1 expression — ESCA

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