Across TCGA patient cohorts, GMFB RNA expression is significantly associated with the protein abundance of many other proteins, with 10,789 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GMFB-associated proteins across cancer lineages are CDC42BPB, PPP2R5E, and NUMB. Each is linked with GMFB in more than 4 cancer types. Because this analysis shows association rather than direction, both GMFB-to-partner and partner-to-GMFB results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GMFB→partner) and Y-score (partner→GMFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDC42BPB →	+0.226	+0.454	<.001	<.001	3	5
GBM	PPP2R5E →	+0.311	+0.769	<.001	<.001	3	5
CCRCC	NUMB →	+0.181	+0.302	.004	.005	3	4
LUAD	WDHD1 →	+0.628	+0.357	<.001	.001	3	4
UCEC	TMX1 →	+0.425	+0.361	.006	.002	2	5
GBM	PPM1A →	+0.191	+0.742	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,789 associations by consensus.

Exploration

GMFB survival (RNA) · tumor vs normal (RNA) · all GMFB data types