GMEB2

Across TCGA patient cohorts, GMEB2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,385 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GMEB2-associated genes across cancer lineages are PCMTD2, CTSL, and DCAF1. Each is linked with GMEB2 in more than 4 cancer types. Because this analysis shows association rather than direction, both GMEB2-to-partner and partner-to-GMEB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GMEB2 versus PCMTD2 in GBM, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GMEB2→partner) and Y-score (partner→GMEB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PCMTD2 →	+0.677	+0.259	.001	.007	3	5
LUAD	CTSL →	-0.677	-0.229	<.001	<.001	3	4
UCEC	DCAF1 →	+0.447	+0.214	.004	.001	3	4
OV	FERMT3 →	-0.716	-0.345	.002	.002	3	4
OV	CCR1 →	-0.911	-0.365	<.001	.001	3	4
GBM	CD14 →	-1.144	-0.301	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,385 associations by consensus.

GMEB2 vs PCMTD2 — GBM

Explore this scatter interactively →