GMDS

Across TCGA cell cohorts, GMDS RNA expression is significantly associated with the RNA expression of many other genes, with 8,812 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GMDS-associated genes across cancer lineages are SH3BGRL2, AGR2, and DSP. Each is linked with GMDS in more than 8 cancer types. Because this analysis shows association rather than direction, both GMDS-to-partner and partner-to-GMDS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GMDS versus SH3BGRL2 in STOMACH, with a Pearson correlation of 0.76.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GMDS→partner) and Y-score (partner→GMDS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SH3BGRL2 →	+2.506	+1.932	<.001	<.001	3	9
STOMACH	AGR2 →	+6.245	+2.042	<.001	<.001	3	8
LUNG_SCLC	DSP →	+3.403	+1.511	<.001	<.001	3	8
LUNG_SCLC	EPCAM →	+4.258	+1.072	<.001	<.001	3	8
OVARY	WRNIP1 →	+0.930	+1.261	<.001	<.001	2	9
STOMACH	MAP7 →	+2.212	+1.811	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,812 associations by consensus.

GMDS vs SH3BGRL2 — STOMACH

Explore this scatter interactively →