GMCL2

Across TCGA patient cohorts, GMCL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,687 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GMCL2-associated GO terms across cancer lineages are Regulation of translational initiation, Regulation of organelle assembly, and Transcription by RNA polymerase III. Each is linked with GMCL2 in more than 24 cancer types. Because this analysis shows association rather than direction, both GMCL2-to-partner and partner-to-GMCL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translational initiation grouped by GMCL2-low versus GMCL2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GMCL2→partner) and Y-score (partner→GMCL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of translational initiation →	+0.069	+0.207	<.001	<.001	3	25
ESCA	Regulation of organelle assembly →	+0.061	+0.186	<.001	<.001	3	24
STAD	Transcription by RNA polymerase III →	+0.061	+0.199	<.001	<.001	3	24
STAD	RNA 3'-end processing →	+0.067	+0.213	<.001	<.001	3	23
STAD	Negative regulation of TOR signaling →	+0.060	+0.196	<.001	<.001	3	23
STAD	Protein-containing complex disassembly →	+0.055	+0.183	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,687 associations by consensus.

Regulation of translational initiation by GMCL2 expression — STAD

Explore this box plot interactively →