GMCL2

Across TCGA cell cohorts, GMCL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,587 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GMCL2-associated GO terms across cancer lineages are Promoter clearance during DNA-templated transcription, RNA polymerase II promoter clearance, and Post-transcriptional gene silencing. Each is linked with GMCL2 in more than 8 cancer types. Because this analysis shows association rather than direction, both GMCL2-to-partner and partner-to-GMCL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Promoter clearance during DNA-templated transcription grouped by GMCL2-low versus GMCL2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GMCL2→partner) and Y-score (partner→GMCL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Promoter clearance during DNA-templated transcription →	+0.121	+0.024	.003	.002	3	9
SOFT_TISSUE	RNA polymerase II promoter clearance →	+0.121	+0.024	.003	.002	3	9
BONE	Post-transcriptional gene silencing →	+0.060	+0.027	.004	.002	3	9
LUNG_NSCLC_LUSC	Peptidyl-serine phosphorylation →	+0.071	+0.031	<.001	<.001	3	9
BONE	Negative regulation of gene expression, epigenetic →	+0.064	+0.031	.009	<.001	3	9
BONE	Pre-mRNA catabolic process →	+0.192	+0.028	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,587 associations by consensus.

Promoter clearance during DNA-templated transcription by GMCL2 expression — SOFT_TISSUE

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