GMCL1

Across TCGA patient cohorts, GMCL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,365 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GMCL1-associated proteins across cancer lineages are CDC73, PAXBP1, and MCM2_S139. Each is linked with GMCL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both GMCL1-to-partner and partner-to-GMCL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GMCL1 versus CDC73 in LSCC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GMCL1→partner) and Y-score (partner→GMCL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CDC73 →	+0.220	+0.600	<.001	<.001	3	6
LSCC	PAXBP1 →	+0.305	+0.657	<.001	<.001	3	6
LSCC	MCM2_S139 →	+0.912	+0.895	<.001	<.001	3	5
HNSC	NUP188 →	+0.140	+0.551	<.001	<.001	3	5
LSCC	PAF1 →	+0.238	+0.568	<.001	<.001	3	5
UCEC	POGK →	+0.339	+0.417	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,365 associations by consensus.

GMCL1 vs CDC73 — LSCC

Explore this scatter interactively →