Across TCGA patient cohorts, GM2A protein abundance is significantly associated with the protein abundance of many other proteins, with 16,835 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GM2A-associated proteins across cancer lineages are FUCA1, HEXA, and PSAP. Each is linked with GM2A in more than 7 cancer types. Because this analysis shows association rather than direction, both GM2A-to-partner and partner-to-GM2A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GM2A→partner) and Y-score (partner→GM2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FUCA1 →	+0.810	+0.797	<.001	<.001	3	8
COAD	HEXA →	+0.458	+0.575	<.001	<.001	3	8
GBM	PSAP →	+0.630	+0.658	<.001	<.001	3	8
LUAD	NPC2 →	+0.730	+0.465	<.001	<.001	3	8
COAD	CTSZ →	+0.817	+0.722	<.001	<.001	3	7
GBM	GRN →	+1.159	+0.616	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,835 associations by consensus.

Exploration

GM2A survival (RNA) · tumor vs normal (RNA) · all GM2A data types