Across TCGA patient cohorts, GM2A mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GM2A-associated genes across cancer lineages are Fibroblasts, CD8+ Tem, and Neutrophils. Each is linked with GM2A in more than 1 cancer types. Because this analysis shows association rather than direction, both GM2A-to-partner and partner-to-GM2A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GM2A→partner) and Y-score (partner→GM2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Fibroblasts →	+0.025	+5.721	.044	.036	3	1
UCEC	CD8+ Tem →	+0.002	+5.258	.002	.029	3	1
UCEC	Neutrophils →	+0.018	+2.166	.001	.040	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

GM2A survival (RNA) · tumor vs normal (RNA) · all GM2A data types