GLYR1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GLYR1 mutation is significantly associated with the RNA expression of many other genes, with 3,694 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLYR1-associated genes across cancer lineages are LINC01751, MIR3155A, and SNX3P1Y. Each is linked with GLYR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GLYR1-to-partner and partner-to-GLYR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01751 grouped by GLYR1-low versus GLYR1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLYR1→partner) and Y-score (partner→GLYR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCLINC01751 →+0.020+4.384<.001.00833
CESCMIR3155A →+0.630+3.934<.001.00532
UCECSNX3P1Y →+0.067+3.893<.001.00632
UCECDHRS2 →+1.032+2.480<.001<.00132
UCECSLPI →-1.646-2.783<.001.00332
UCECCACNA1A →-0.442-1.715.004.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,694 associations by consensus.

LINC01751 by GLYR1 expression — CESC

Box plot of LINC01751 in GLYR1-low vs GLYR1-high samples in CESC.

Explore this box plot interactively →

Exploration