GLYR1

Across TCGA cell cohorts, GLYR1 mutation is significantly associated with the RNA expression of many other genes, with 1,827 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GLYR1-associated genes across cancer lineages are MGARP, NUDT10, and FABP9. Each is linked with GLYR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLYR1-to-partner and partner-to-GLYR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MGARP grouped by GLYR1-low versus GLYR1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLYR1→partner) and Y-score (partner→GLYR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MGARP →	+0.104	+3.169	.002	.005	3	2
BLOOD_Leukemia	NUDT10 →	+1.065	+3.491	.001	.009	3	2
UPPER_AERODIGESTIVE_TRACT	FABP9 →	+0.045	+4.357	<.001	.006	3	1
LARGE_INTESTINE	PES1 →	+0.471	+4.215	.002	<.001	3	1
LARGE_INTESTINE	ESS2 →	+0.497	+2.265	.002	.001	3	1
LARGE_INTESTINE	LRP5L →	+0.643	+2.949	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,827 associations by consensus.

MGARP by GLYR1 expression — LARGE_INTESTINE

Explore this box plot interactively →