GLYCTK

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GLYCTK protein abundance is significantly associated with the RNA expression of many other genes, with 4,170 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GLYCTK-associated genes across cancer lineages are PHF21A, UBXN7, and MTPN. Each is linked with GLYCTK in more than 2 cancer types. Because this analysis shows association rather than direction, both GLYCTK-to-partner and partner-to-GLYCTK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GLYCTK versus PHF21A in GBM, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLYCTK→partner) and Y-score (partner→GLYCTK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMPHF21A →-0.375-0.805.004.00433
GBMUBXN7 →-0.526-0.997<.001.00133
UCECMTPN →-0.357-0.464.003.00332
GBMSLC49A4 →-0.445-0.778<.001.00132
UCECPRDM5 →-1.145-0.489<.001.00132
UCECFBXL7 →-0.806-0.402.003<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,170 associations by consensus.

GLYCTK vs PHF21A — GBM

Per-sample scatter of GLYCTK vs PHF21A in GBM (Pearson r = -0.34).

Explore this scatter interactively →

Exploration