GLYCTK

Across TCGA patient cohorts, GLYCTK mutation is significantly associated with the RNA expression of many other genes, with 596 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLYCTK-associated genes across cancer lineages are MIR6738, KRTAP6-2, and MIR6795. Each is linked with GLYCTK in more than 1 cancer types. Because this analysis shows association rather than direction, both GLYCTK-to-partner and partner-to-GLYCTK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6738 grouped by GLYCTK-low versus GLYCTK-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLYCTK→partner) and Y-score (partner→GLYCTK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR6738 →	+0.380	+2.164	.004	.004	3	2
BLCA	KRTAP6-2 →	+0.168	+6.618	<.001	.001	3	2
HNSC	MIR6795 →	+0.418	+7.954	<.001	.008	3	2
BLCA	MIR4739 →	+0.573	+6.618	<.001	.001	3	2
SKCM	FGD5 →	-0.706	-3.430	.002	.005	3	2
CESC	RPL12P23 →	+0.095	+4.816	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 596 associations by consensus.

MIR6738 by GLYCTK expression — SKCM

Explore this box plot interactively →