GLYCTK

Across TCGA cell cohorts, GLYCTK mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GLYCTK-associated genes across cancer lineages are ELOA3DP, OR13G1, and WNT8A. Each is linked with GLYCTK in more than 1 cancer types. Because this analysis shows association rather than direction, both GLYCTK-to-partner and partner-to-GLYCTK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELOA3DP grouped by GLYCTK-low versus GLYCTK-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLYCTK→partner) and Y-score (partner→GLYCTK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ELOA3DP →	+0.039	+4.273	<.001	.006	3	1
LARGE_INTESTINE	OR13G1 →	+0.024	+4.415	<.001	.007	3	1
LARGE_INTESTINE	WNT8A →	+0.028	+5.217	<.001	<.001	3	1
OVARY	OR12D3 →	+0.016	+5.807	<.001	.001	3	1
OVARY	DEFA6 →	+0.111	+5.196	.004	.005	3	1
BLOOD_Leukemia	USP29 →	+0.006	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

ELOA3DP by GLYCTK expression — LARGE_INTESTINE

Explore this box plot interactively →