GLYCTK-AS1

Across TCGA pan-cancer cohorts, GLYCTK-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated GLYCTK-AS1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GLYCTK-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated GLYCTK-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LGG show a favorable association.

UCEC, LGG, and HNSC are the cancer types where GLYCTK-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	IV	0.930	0.422	.003	54	view →
LGG	OS	Median	All	0.512	0.379	<.001	45	view →
HNSC	OS	Quartile	All	0.742	0.625	.010	37	view →
BRCA	OS	Median	II,III,IV	0.977	0.939	<.001	34	view →
KIRC	DFS	Median	IV	0.220	0.429	.003	24	view →
THCA	DFS	Quartile	III,IV	0.519	0.855	.010	14	view →
PCPG	OS	Median	All	0.939	1.000	.025	14	view →
ESCA	OS	Tertile	II,III,IV	0.464	1.000	.037	12	view →
ACC	OS	Median	III,IV	0.191	0.750	.005	12	view →
READ	OS	Median	III,IV	0.971	0.818	.004	11	view →
MESO	DFS	Quartile	IV	0.079	0.563	.009	9	view →
UVM	DFS	Quartile	III,IV	0.137	0.728	<.001	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

GLYCTK-AS1–UCEC (DFS)

Open the UCEC breakdown →