Across TCGA cell cohorts, GLYATL3 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GLYATL3-associated genes across cancer lineages are FAM47A, KRTAP4-6, and TMCO5A. Each is linked with GLYATL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLYATL3-to-partner and partner-to-GLYATL3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLYATL3→partner) and Y-score (partner→GLYATL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FAM47A →	+0.041	+4.922	<.001	.009	3	1
BLOOD_Leukemia	KRTAP4-6 →	+0.024	+5.201	.002	.006	3	1
LARGE_INTESTINE	TMCO5A →	+0.019	+4.415	<.001	.007	3	1
LARGE_INTESTINE	CCL18 →	+0.097	+4.415	<.001	.007	3	1
LARGE_INTESTINE	CD300H →	+0.033	+4.415	<.001	.007	3	1
LUNG_SCLC	GDF2 →	+0.017	+4.643	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

GLYATL3 survival (RNA) · tumor vs normal (RNA) · all GLYATL3 data types