GLYATL2

Across TCGA patient cohorts, GLYATL2 mutation is significantly associated with the RNA expression of many other genes, with 3,341 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLYATL2-associated genes across cancer lineages are MIR1227, MTCO3P42, and MRPL46. Each is linked with GLYATL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLYATL2-to-partner and partner-to-GLYATL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1227 grouped by GLYATL2-low versus GLYATL2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLYATL2→partner) and Y-score (partner→GLYATL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR1227 →	+0.408	+5.618	<.001	.002	3	2
BLCA	MTCO3P42 →	+0.096	+4.788	<.001	.006	3	2
UCEC	MRPL46 →	+0.339	+2.914	.001	.001	3	2
UCEC	MYL12BP1 →	+0.501	+1.939	<.001	.009	3	2
SKCM	RN7SL376P →	+0.075	+1.367	.002	.005	3	2
ESCA	RNA5SP228 →	+0.367	+5.450	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,341 associations by consensus.

MIR1227 by GLYATL2 expression — BLCA

Explore this box plot interactively →