GLYATL2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GLYATL2 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GLYATL2-associated genes across cancer lineages are OR2T29, SMCP, and TMEM252. Each is linked with GLYATL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLYATL2-to-partner and partner-to-GLYATL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2T29 grouped by GLYATL2-low versus GLYATL2-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLYATL2→partner) and Y-score (partner→GLYATL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OESOPHAGUSOR2T29 →+0.116+4.906<.001.00631
LUNG_SCLCSMCP →+0.038+4.058<.001.00731
LUNG_SCLCTMEM252 →+0.479+3.788.006.00631
LUNG_SCLCKRTAP20-2 →+0.630+3.817<.001.00431
LUNG_SCLCKRTAP19-2 →+0.102+4.058<.001.00731
LUNG_SCLCCYP2B6 →+0.234+3.925<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

OR2T29 by GLYATL2 expression — OESOPHAGUS

Box plot of OR2T29 in GLYATL2-low vs GLYATL2-high samples in OESOPHAGUS.

Explore this box plot interactively →

Exploration