GLYATL1

Across TCGA cell cohorts, GLYATL1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GLYATL1-associated genes across cancer lineages are TPPP2, TAAR1, and SPRR1A. Each is linked with GLYATL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLYATL1-to-partner and partner-to-GLYATL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TPPP2 grouped by GLYATL1-low versus GLYATL1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLYATL1→partner) and Y-score (partner→GLYATL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	TPPP2 →	+0.070	+4.217	<.001	.001	3	1
BLOOD_Leukemia	TAAR1 →	+0.021	+4.922	<.001	.009	3	1
BLOOD_Leukemia	SPRR1A →	+0.287	+5.201	<.001	.006	3	1
BLOOD_Lymphoma	KRTAP5-11 →	+0.029	+5.209	<.001	.005	3	1
LARGE_INTESTINE	OR1C1 →	+0.076	+3.684	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

TPPP2 by GLYATL1 expression — SKIN

Explore this box plot interactively →