GLYAT

Across TCGA patient cohorts, GLYAT RNA expression is significantly associated with the go_rna of many other GO terms, with 7,077 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GLYAT-associated GO terms across cancer lineages are Positive regulation of canonical Wnt signaling pathway, Regulation of proteolysis involved in protein catabolic process, and Positive regulation of ubiquitin-dependent protein catabolic process. Each is linked with GLYAT in more than 12 cancer types. Because this analysis shows association rather than direction, both GLYAT-to-partner and partner-to-GLYAT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of canonical Wnt signaling pathway grouped by GLYAT-low versus GLYAT-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLYAT→partner) and Y-score (partner→GLYAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of canonical Wnt signaling pathway →	+0.057	+0.064	<.001	<.001	3	12
ESCA	Regulation of proteolysis involved in protein catabolic process →	+0.073	+0.081	.001	.004	3	12
STAD	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.057	+0.061	<.001	<.001	3	12
STAD	Phospholipid biosynthetic process →	+0.080	+0.097	<.001	<.001	3	12
STAD	Protein-RNA complex organization →	+0.061	+0.064	<.001	<.001	3	11
STAD	Positive regulation of intracellular protein transport →	+0.067	+0.065	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,077 associations by consensus.

Positive regulation of canonical Wnt signaling pathway by GLYAT expression — STAD

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