GLYAT

Across TCGA cell cohorts, GLYAT mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GLYAT-associated genes across cancer lineages are C20orf85, OR1L4, and H2BC1. Each is linked with GLYAT in more than 1 cancer types. Because this analysis shows association rather than direction, both GLYAT-to-partner and partner-to-GLYAT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C20orf85 grouped by GLYAT-low versus GLYAT-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLYAT→partner) and Y-score (partner→GLYAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	C20orf85 →	+0.107	+5.954	<.001	<.001	3	1
SOFT_TISSUE	OR1L4 →	+0.053	+4.369	<.001	.008	3	1
SOFT_TISSUE	H2BC1 →	+0.325	+4.977	<.001	.002	3	1
SOFT_TISSUE	H2AC1 →	+0.145	+4.977	<.001	.002	3	1
SOFT_TISSUE	OR4D6 →	+0.035	+4.977	<.001	.002	3	1
SOFT_TISSUE	OR51L1 →	+0.027	+4.369	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

C20orf85 by GLYAT expression — SOFT_TISSUE

Explore this box plot interactively →