GLULP4

Across TCGA pan-cancer cohorts, GLULP4 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of GLULP4’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where GLULP4 RNA is repressed in tumor relative to normal tissue. In most cancer types GLULP4 is over-expressed in tumor, although a few such as THCA and STAD show the opposite, repressed pattern.

THCA, STAD, and LIHC are the cancer types where GLULP4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GLULP4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	All	−0.277	<.001	9	view →
STAD	All	All	−0.208	.022	6	view →
LIHC	Male	All	+0.345	<.001	4	view →
COAD	Female	All	+0.237	.006	4	view →
BLCA	Female	IV	−0.273	.005	3	view →
PAAD	All	All	−0.329	.016	2	view →
KIRC	All	All	+0.045	.010	2	view →
ESCA	All	All	−0.532	.006	1	view →
LUSC	Female	III,IV	+0.110	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

GLULP4–THCA

Open the THCA breakdown →