GLUL

Across TCGA pan-cancer cohorts, GLUL mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated GLUL data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher GLUL mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GLUL expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

COAD, PDAC, and CCRCC are the cancer types where GLUL mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.879	1.000	.019	48	view →
PDAC	OS	Quartile	III,IV	0.178	0.736	<.001	35	view →
CCRCC	DFS	Median	II,III,IV	0.235	0.887	.005	12	view →
UCEC	OS	Quartile	All	1.000	0.789	.007	10	view →
LSCC	OS	Quartile	II,III,IV	0.595	0.893	.025	2	view →
GBM	DFS	Median	All	0.292	0.443	.018	2	view →
HNSC	OS	Median	All	0.991	0.945	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

GLUL–COAD (DFS)

Open the COAD breakdown →