GLUL

Across TCGA cell cohorts, GLUL mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GLUL-associated genes across cancer lineages are MMP26, REG1B, and SPINK9. Each is linked with GLUL in more than 1 cancer types. Because this analysis shows association rather than direction, both GLUL-to-partner and partner-to-GLUL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP26 grouped by GLUL-low versus GLUL-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLUL→partner) and Y-score (partner→GLUL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MMP26 →	+0.039	+3.632	<.001	.003	3	1
LARGE_INTESTINE	REG1B →	+2.047	+3.196	.001	.007	3	1
SKIN	SPINK9 →	+0.058	+5.415	<.001	.004	3	1
STOMACH	RD3 →	+0.114	+4.700	<.001	.007	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MMP26 by GLUL expression — LARGE_INTESTINE

Explore this box plot interactively →