GLUD1P4

Across TCGA pan-cancer cohorts, GLUD1P4 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated GLUD1P4 data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher GLUD1P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GLUD1P4 expression acts as an unfavorable survival marker, although some lineages such as SKCM and ESCA show a favorable association.

CHOL, BLCA, and THCA are the cancer types where GLUD1P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	OS	Tertile	All	0.024	0.728	<.001	108	view →
BLCA	DFS	Tertile	III,IV	0.171	0.478	.004	57	view →
THCA	DFS	Tertile	II,III,IV	0.577	0.854	<.001	54	view →
BRCA	OS	Tertile	II,III,IV	0.782	0.917	.003	48	view →
THYM	DFS	Tertile	II,III,IV	0.145	0.873	<.001	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	27	view →
SKCM	DFS	Tertile	III,IV	1.000	0.483	.011	21	view →
LUSC	OS	Tertile	All	0.216	0.519	.015	15	view →
ESCA	OS	Tertile	III,IV	0.657	0.359	.036	12	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
COAD	OS	Tertile	All	0.498	0.802	.049	9	view →
LGG	DFS	Tertile	All	0.977	0.811	.035	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

GLUD1P4–CHOL (OS)

Open the CHOL breakdown →