GLTPD2

Across TCGA patient cohorts, GLTPD2 mutation is significantly associated with the RNA expression of many other genes, with 56 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLTPD2-associated genes across cancer lineages are OR8B8, TSEN2P1, and POTED. Each is linked with GLTPD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLTPD2-to-partner and partner-to-GLTPD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8B8 grouped by GLTPD2-low versus GLTPD2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLTPD2→partner) and Y-score (partner→GLTPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR8B8 →	+0.047	+5.899	<.001	.002	3	2
COAD	TSEN2P1 →	+0.195	+5.602	<.001	<.001	3	2
BLCA	POTED →	+0.032	+6.444	<.001	.001	3	1
BLCA	ZNF72P →	+0.028	+5.497	<.001	.004	3	1
BLCA	RNU6-934P →	+0.404	+5.497	<.001	.004	3	1
BLCA	RNU6-898P →	+0.302	+5.106	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

OR8B8 by GLTPD2 expression — BLCA

Explore this box plot interactively →