GLTPD2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GLTPD2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GLTPD2-associated genes across cancer lineages are GFRA4, CHP2, and BHLHA9. Each is linked with GLTPD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLTPD2-to-partner and partner-to-GLTPD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GFRA4 grouped by GLTPD2-low versus GLTPD2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLTPD2→partner) and Y-score (partner→GLTPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEGFRA4 →+0.014+4.169.003.00231
SOFT_TISSUECHP2 →+0.065+3.736.009.00831
SOFT_TISSUEBHLHA9 →+0.022+4.392<.001.00431
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

GFRA4 by GLTPD2 expression — SOFT_TISSUE

Box plot of GFRA4 in GLTPD2-low vs GLTPD2-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration