GLTPD2

Across TCGA cell cohorts, GLTPD2 mutation is significantly associated with the mutation status of many other genes, with 69 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GLTPD2-associated genes across cancer lineages are SLX4, MAN1A2, and RYR2. Each is linked with GLTPD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLTPD2-to-partner and partner-to-GLTPD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLX4 grouped by GLTPD2-low versus GLTPD2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLTPD2→partner) and Y-score (partner→GLTPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	SLX4 →	+2.985	+3.562	.008	.008	1	1
SOFT_TISSUE	MAN1A2 →	+5.307	+4.651	<.001	<.001	1	1
SOFT_TISSUE	RYR2 →	+2.137	+3.781	.008	.008	1	1
SOFT_TISSUE	NPY4R →	+4.307	+4.307	.001	.001	1	1
SOFT_TISSUE	MUC12 →	+2.985	+3.562	.008	.008	1	1
SOFT_TISSUE	PLXNA4 →	+2.985	+3.562	.008	.008	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

SLX4 by GLTPD2 expression — SOFT_TISSUE

Explore this box plot interactively →