GLTP

Across TCGA cell cohorts, GLTP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,186 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GLTP-associated GO terms across cancer lineages are Regulation of glucosylceramide biosynthetic process, Endolysosomal toll-like receptor signaling pathway, and Endosomal transport. Each is linked with GLTP in more than 13 cancer types. Because this analysis shows association rather than direction, both GLTP-to-partner and partner-to-GLTP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of glucosylceramide biosynthetic process grouped by GLTP-low versus GLTP-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GLTP→partner) and Y-score (partner→GLTP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of glucosylceramide biosynthetic process →	+0.135	+0.839	<.001	<.001	3	14
SOFT_TISSUE	Endolysosomal toll-like receptor signaling pathway →	+0.107	+0.735	<.001	.001	3	9
BLOOD_Lymphoma	Endosomal transport →	+0.026	+0.519	.003	.001	3	9
OVARY	Endocytic recycling →	+0.055	+0.606	<.001	<.001	3	8
BLOOD_Lymphoma	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.090	+0.577	<.001	<.001	3	8
LIVER	Positive regulation of postsynaptic membrane organization →	+0.190	+1.035	<.001	.004	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,186 associations by consensus.

Regulation of glucosylceramide biosynthetic process by GLTP expression — PANCREAS

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