GLT8D1

Across TCGA pan-cancer cohorts, GLT8D1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated GLT8D1 data layer compared with 20 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GLT8D1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GLT8D1 expression acts as an unfavorable survival marker, although some lineages such as COAD and LUAD show a favorable association.

UCEC, COAD, and LSCC are the cancer types where GLT8D1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	II,III,IV	0.465	1.000	.005	16	view →
COAD	DFS	Tertile	II,III,IV	1.000	0.914	.048	12	view →
LSCC	DFS	Tertile	II,III,IV	0.647	0.901	.015	7	view →
LUAD	OS	Quartile	III,IV	0.842	0.355	.032	4	view →
HNSC	DFS	Median	All	0.698	1.000	.020	4	view →
CCRCC	DFS	Tertile	All	0.868	0.699	.026	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

GLT8D1–UCEC (DFS)

Open the UCEC breakdown →