GLT8D1

Across TCGA patient cohorts, GLT8D1 mutation is significantly associated with the RNA expression of many other genes, with 446 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLT8D1-associated genes across cancer lineages are SDR42E1P1, MYO19, and RHOXF2. Each is linked with GLT8D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLT8D1-to-partner and partner-to-GLT8D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SDR42E1P1 grouped by GLT8D1-low versus GLT8D1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLT8D1→partner) and Y-score (partner→GLT8D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SDR42E1P1 →	+0.037	+7.057	<.001	.009	3	1
UCEC	MYO19 →	+0.750	+3.483	<.001	.002	3	1
BRCA	RHOXF2 →	+0.296	+3.797	<.001	.007	3	1
BRCA	RNA5SP65 →	+0.510	+4.683	<.001	.005	3	1
BRCA	RNU6-7 →	+0.456	+4.217	.001	.004	3	1
BRCA	TRDD1 →	+0.545	+7.057	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 446 associations by consensus.

SDR42E1P1 by GLT8D1 expression — BRCA

Explore this box plot interactively →