GLT8D1

Across TCGA patient cohorts, GLT8D1 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLT8D1-associated genes across cancer lineages are FoxM1, Tuberin, and Rab25. Each is linked with GLT8D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLT8D1-to-partner and partner-to-GLT8D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by GLT8D1-low versus GLT8D1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLT8D1→partner) and Y-score (partner→GLT8D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.288	+3.169	.042	.020	3	1
UCEC	Tuberin →	+0.382	+3.169	.009	.020	3	1
UCEC	Rab25 →	-0.626	-3.169	<.001	.020	1	1
UCEC	VHL →	-1.364	-3.169	<.001	.020	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

FoxM1 by GLT8D1 expression — UCEC

Explore this box plot interactively →