Across TCGA patient cohorts, GLT6D1 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GLT6D1-associated genes across cancer lineages are Cyclin-E2, Heregulin, and JNK_pT183_Y185. Each is linked with GLT6D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GLT6D1-to-partner and partner-to-GLT6D1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GLT6D1→partner) and Y-score (partner→GLT6D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-E2 →	+0.147	+1.700	.039	.044	3	2
UCEC	Heregulin →	-0.124	-1.700	.017	.044	3	1
UCEC	JNK_pT183_Y185 →	-0.175	-3.000	.014	.036	3	1
UCEC	Mre11 →	-0.083	-3.143	.022	.018	3	1
UCEC	Rab25 →	-0.388	-2.906	.005	.001	3	1
UCEC	Annexin-1 →	+0.477	+2.189	.032	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

GLT6D1 survival (RNA) · tumor vs normal (RNA) · all GLT6D1 data types